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Moles & Skin Cancer

What Are Moles and When Should You Be Concerned?

April 2026
5 min read
What Are Moles and When Should You Be Concerned?

Moles are one of the most common skin growths I evaluate in my dermatology practice. Most moles are benign and harmless, but it's important to understand when a mole might warrant professional attention.

Moles are collections of melanocytes (pigment-producing cells) that cluster together. They can appear anywhere on the body and typically develop during childhood and early adulthood. Most people have 10-40 moles by adulthood.

Moles can vary in appearance. Some are flat, others are raised. They can be brown, black, or even flesh-colored. Size can range from a few millimeters to over a centimeter. Most moles are stable and don't change significantly over time.

However, certain changes in a mole warrant professional evaluation. I use the ABCDE rule to help patients identify potentially concerning moles:

Asymmetry: One half of the mole doesn't match the other half. Border irregularity: The edges are jagged, scalloped, or poorly defined. Color variation: The mole contains multiple colors or uneven color distribution. Diameter: The mole is larger than a pencil eraser (about 6mm). Evolving: The mole is changing in size, shape, or color.

If you notice any of these characteristics, schedule a dermatology evaluation promptly. Early detection of melanoma significantly improves treatment outcomes.

Other changes that warrant evaluation include moles that become itchy, painful, or bleed. These could indicate melanoma or other skin conditions requiring treatment.

I recommend regular self-examination of your moles. Take photos of your moles to track changes over time. This is particularly important if you have many moles, fair skin, or a family history of melanoma.

If you're concerned about any moles, don't hesitate to schedule a professional evaluation. It's better to have a benign mole evaluated than to miss a potentially serious condition.

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